I would see Markkula's comments less as medical comment, and rather... hmm.. "underground comment". hah. When you look at the history of underground cultures, it's very often been rebellious, frustrated, FTW, No Future!, morally questionable behavior, and so on. All in all, something that indicates not fitting in to system, but some sort of resistance. It is just that I do not think "good mental health" standard, is that psychotic delusional reality that society often offers.
Therefore I see Markkula blurting out "mental health problem" more as indication that people tend to deviate from supposedly virtuous qualities presented in mainstream society.