If we talk about physicality of sounds, rather than live performance aspect a'la spastic movement... Then I'd agree, that most of noise I value the highest, are sounds from physical acts or something what happens with direct connection to body.
For example, when I think of ambient or drone music of some sort, nothing is more boring for me than someone with keyboards or software. Making seemingly nice waves of sound, but lacking utterly physical aspect. Some may ask what is the difference of playing cymbal with bow, or letting reverb drenched guitar feedback with little guidance vs. pushing key on keyboard. Simple explanation would be: Personal preference!
Perhaps moment when someone really starts modulating (hehe..), synthesizer can be interesting, but it most often still seems "just a synth", compared to entire existence of sounds that can be made or are happening.
I perhaps have talked about it many times before, but some sounds have intrinsic nature of being loud. Synthesizer is only as loud as you amplify it. Impression of recording changes when volume is less. Same sound, no matter if distorted and raw, may be just quiet electronic signal if you listen it at low volume.
Human yelling, explosion, car-crash, metal junk being thrown around, etc. It may give impression of loud and abrasive, despite listened at low volume from record. One could say, document of loud situation. This is also difference one may often hear from tiny metal object run through "hall reverb" vs. actually big and physically demanding object. Shake-box via distortion vs. 3 x 6 metric scrap metal object. Physical reality may offer possibilities very far from simulations.
